Healthy lifestyle behaviors may lower risk for dementia in type 2 diabetes
September 21, 2022
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Source/Disclosures
Published by:
Boonpor J, et al. SO 319. Offered at: European Affiliation for the Analyze of Diabetes Yearly Assembly Sept. 19-23, 2022 Stockholm (hybrid conference).
Disclosures:
Boonpor stories no applicable fiscal disclosures.
Dwelling a much healthier way of life can decreased the threat for dementia for grownups with type 2 diabetes, in accordance to a speaker at the European Affiliation for the Study of Diabetic issues once-a-year assembly.
“We know style 2 diabetes is a possibility element for dementia,” Jirapitcha Boonpor, a PhD scholar in the School of Cardiovascular and Metabolic Health and fitness at the University of Glasgow, U.K., explained during a presentation. “Thirty-five percent of dementia risk is brought about by modifiable threat elements. However, the url between way of life, type 2 diabetic issues and dementia is unclear. This examine aims to investigate to what extent the association between kind 2 diabetes and dementia possibility is modified by way of living.”
Scientists performed a prospective cohort examine of 445,364 grown ups in the Uk Biobank (necessarily mean age, 55.6 a long time 54.6{b574a629d83ad7698d9c0ca2d3a10ad895e8e51aa97c347fc42e9508f0e4325d} girls). Grownups self-described regardless of whether they experienced type 2 diabetic issues. Incident dementia was determined from inpatient healthcare facility documents. Scientists analyzed nine self-documented way of living behaviors: Tv viewing time, bodily exercise, slumber period, smoking cigarettes position, alcoholic beverages intake and having processed meat, crimson meat, fruits and veggies, and oily fish. An unhealthy chance rating was calculated, with a rating of zero described as getting the healthiest life-style and a rating of seven described as acquiring the minimum wholesome way of living.
The cohort was adopted for a median of 9.1 several years. Grown ups with form 2 diabetic issues had a higher hazard for building dementia than those with out diabetic issues (HR = 1.33 95{b574a629d83ad7698d9c0ca2d3a10ad895e8e51aa97c347fc42e9508f0e4325d} CI, 1.16-1.53 P < .0001). Adults who had an unhealthy lifestyle risk score of seven had an increased risk for dementia compared with those with a risk score of zero (HR = 1.65 95{b574a629d83ad7698d9c0ca2d3a10ad895e8e51aa97c347fc42e9508f0e4325d} CI, 1.08-2.52 P = .02).
Adults without type 2 diabetes and the healthiest lifestyle had a lower risk for dementia than those without type 2 diabetes and the least healthy lifestyle (HR = 0.72 95{b574a629d83ad7698d9c0ca2d3a10ad895e8e51aa97c347fc42e9508f0e4325d} CI, 0.59-0.9 P = .003). Similarly, adults with type 2 diabetes and the healthiest lifestyle risk score had a decreased risk for dementia compared with adults with diabetes and the least healthy lifestyle (HR = 0.55 95{b574a629d83ad7698d9c0ca2d3a10ad895e8e51aa97c347fc42e9508f0e4325d} CI, 0.38-0.92 P = .003).
“Having type 2 diabetes increases the chance of developing dementia, but this could be reduced if people with type 2 diabetes comply with healthy lifestyle behaviors,” Boonpor said. “There is no treatment for dementia, so prevention is more important.”
