March 3, 2024

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WHO and MPP announce agreement with NIH for COVID-19 health technologies

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WHO and MPP announce agreement with NIH for COVID-19 health technologies

Technological know-how Access Pool (C-Tap) and the Medications Patent Pool (MPP) these days
finalized a licensing arrangement with the United States National Institutes of
Well being (NIH) for the enhancement of quite a few ground breaking therapeutics,
early-stage vaccines and diagnostic tools for COVID-19.

The licenses, which are transparent,
world and non-unique, will enable brands
from all-around the world to function with MPP and C-Faucet to make these systems
available to folks dwelling in minimal- and center-cash flow nations around the world and support put an
close to the pandemic.

The 11 COVID-19
technologies provided underneath two licences involve the stabilized spike protein
utilised in at the moment obtainable COVID-19 vaccines, investigate equipment for vaccine,
therapeutic and diagnostic advancement as effectively as early-phase vaccine
candidates and diagnostics. The whole listing of the NIH COVID-19 technologies
lined in the agreement is in this article.

“I welcome the generous
contribution NIH has manufactured to C-Tap and its illustration of solidarity and sharing,”
said Dr Tedros Adhanom
Ghebreyesus, WHO
Director-Standard. “Whether it is today’s pandemic or tomorrow’s health
crisis, it’s by sharing and empowering lower-income countries to
manufacture their personal health tools that we can guarantee a healthier future for
all people.”

“We are honoured
to signal these general public overall health-pushed licence agreements with NIH under the
auspices of C-Faucet with the objective of furnishing equitable entry to daily life-saving
overall health merchandise for the most vulnerable in the entire world,” said Charles Gore, MPP
Executive Director.

“NIH were the to start with to
share their patents with MPP for an HIV products back in 2010 when we were made, and we are delighted
to carry on strengthening our partnership. It is clear that MPP’s design performs
throughout different health and fitness systems.”

The announcement was
built nowadays by the US Govt at the 2nd International COVID-19 Summit, co-hosted
by the United States, Belize, Germany, Indonesia and Senegal.

Licensing the NIH
technologies to MPP less than the auspices of C-Faucet will permit better accessibility to
these technologies and ideally direct to the growth of professional products and solutions
that can tackle present-day and long term community wellbeing needs. In most situations,
NIH will not obtain royalties on sales of goods licensed in 49 nations
classified by the United Nations as Minimum Produced International locations.

Introduced in 2020 by the
WHO Director-General and the President of Costa Rica, and supported by 43
Member States, C-TAP aims to facilitate well timed, equitable and inexpensive obtain to
COVID-19 wellbeing products by boosting their creation and source by way of open up,
clear and non-exceptional licensing agreements. MPP provides the licensing know-how to
this initiative and holds the licences.

The 11 technologies

  1. Prefusion spike
    proteins  (Vaccine Development)
  2. Structure-Based
    Design and style of Spike Immunogens  (Exploration Instrument for Vaccine Development)
  3. Pseudotyping
    Plasmid (Study Device for Vaccine Enhancement)
  4. ACE2 Dimer
    construct (Investigation Instrument for Drug Development)
  5. Artificial humanized
    llama nanobody library and related use  (Exploration Tool for
    Drug and Diagnostic Development)
  6. Newcastle Illness Virus-Like
    Particles Exhibiting Prefusion-Stabilized  Spikes (Vaccine
  7. Parainfluenza virus 3 primarily based
    vaccine (Vaccine Prospect)
  8. A VSV-EBOV-Based
    Vaccine (Vaccine Applicant)
  9. RNASEH-Assisted
    Detection Assay for RNA (Diagnostic)
  10. Detection of SARS-CoV-2 and
    other RNA Virus (Diagnostic)
  11. Substantial-Throughput Diagnostic
    Test  (Diagnostic)
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